Epilepsy and eating disorders during pregnancy: Prevalence, complications and birth outcome

نویسندگان

  • Eivind Kolstad
  • Nils Erik Gilhus
  • Gyri Veiby
  • Simone Frizell Reiter
  • Morten Ingvar Lossius
  • Marte Bjørk
چکیده

PURPOSE The aim was to investigate the prevalence of eating disorders and its relation to pregnancy and delivery complications in childbearing women with epilepsy (WWE). METHOD This study is based on The Norwegian Mother and Child Cohort Study (MoBa) linked to the Medical Birth Registry of Norway. Epilepsy was reported in 706 pregnancies. The remaining cohort (n=106,511) served as the reference group. Eating disorders were diagnosed using DSM-IV criteria adjusted for pregnancy. The risk of preeclampsia, gestational hypertension, diabetes and weight gain during pregnancy as well as delivery outcome (small for gestational age, large for gestational age, ponderal index, low APGAR score, small head circumference) were calculated as odds ratios (ORs) with 95% confidence intervals (CIs) adjusted for maternal age, smoking, parity and socioeconomic factors. RESULTS Pregnant WWE were significantly more likely to have binge eating disorder (6.5% vs. 4.7%, p<0.05). WWE and comorbid eating disorders had significantly more preeclampsia (7.9% vs. 3.7%, p<0.05), peripartum depression and/or anxiety (40.4% vs. 17.8%, p<0.001) and operative delivery (38.2% vs. 23.5%, p<0.001) than the reference group without epilepsy or eating disorders. After adjustment for confounders, a significantly increased risk of operative delivery (OR 1.96, CI 1.26-3.05) and peripartum depression and/or anxiety (OR 2.17, CI 1.40-3.36) was demonstrated. CONCLUSION Eating disorders in WWE contribute to the increased risk of pregnancy and delivery complications. Health personnel should be aware of eating disorders in WWE and refer them for treatment before pregnancy.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Complications of Alcohol Use in Pregnancy

Background: Alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  Discussion: Alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. Drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. Alcohol-related birth ...

متن کامل

The prevalence of adverse obstetric outcomes follow of an abnormal maternal serum AFP and NTDs screen positive group

Introduction: Prenatal maternal serum AFP screening tests have some inherent false positive and false negative results. For NTDs Screening test (FTS) false positive rate (FPR) is about 1% and false negative rate (FNR) is 20%. A false positive result encourages by Anomaly scan and invasive diagnostic procedures (that poses lots of stress on women, too), while a false negative result lead to a N...

متن کامل

Pnm-16: The Effect of Pregnancy above 40 Years on The Fetal Health

a:4:{s:10:"Background";s:405:"Women's Health is trying to Priority health programs. A natural event of a woman's life is pregnancy. Highly regard to maternal health during pregnancy, one of the most basic ways maintains health of mother and fetus. Age factors are affecting the outcome of pregnancy. The aim of this study was evaluation of the complications of pregnant women above 40 years referr...

متن کامل

Pregnancy with epilepsy: Obstetric and neonatal outcome of a controlled study

PURPOSE To determine the influence of epilepsy and its treatment on pregnancy and its outcome. DESIGN Controlled, observational study. SETTING National Health Service maternity hospitals in Liverpool and Manchester regions. POPULATION 277 women with epilepsy (WWE) and 315 control women. METHODS WWE were recruited from antenatal clinics. Controls were matched for age and parity but not g...

متن کامل

Obstetric outcome in women with epilepsy: a hospital-based, retrospective study.

OBJECTIVE To report the complications during pregnancy and delivery in women with epilepsy, compared with a control group without epilepsy, with special focus on potential risk factors, such as epilepsy severity and dosage of antiepileptic drugs. DESIGN Hospital-based retrospective study. SETTING Data from pregnancy notification forms and hospital case records. POPULATION Women with a pas...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Seizure

دوره 28  شماره 

صفحات  -

تاریخ انتشار 2015